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Region: South | West | East | Midwest | Final 4 |
| 2018 NCAA Men's Basketball Tournament Bracket - South Region | ||||
| 1st Round | 2nd Round | Sweet 16 | Elite 8 | Final 4 |
| 1.) Virginia | ||||
| 54-74 (F)
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| 16.) UMBC | South Region | |||
| 50-43 (F)
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| 16.) UMBC | ||||
| 9.) Kansas State | ||||
| 8.) Creighton | 58-61 (F)
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| 59-69 (F)
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| 9.) Kansas State | ||||
| 9.) Kansas State | ||||
| 9.) Kansas State | ||||
| 5.) Kentucky | 62-78 (F)
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| 78-73 (F)
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| 5.) Kentucky | ||||
| 95-75 (F)
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| 12.) Davidson | ||||
| 5.) Kentucky | ||||
| 4.) Arizona | ||||
| 68-89 (F)
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| 13.) Buffalo | ||||
| 13.) Buffalo | ||||
| 11.) Loyola Chicago | ||||
| 6.) Miami (FL) | Champion (South Region) |
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| 62-64 (F)
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| 11.) Loyola Chicago | ||||
| 62-63 (F)
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| 11.) Loyola Chicago | ||||
| 11.) Loyola Chicago | ||||
| 3.) Tennessee | 68-69 (F)
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| 73-47 (F)
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| 3.) Tennessee | ||||
| 14.) Wright State | ||||
| 11.) Loyola Chicago | ||||
| 7.) Nevada | ||||
| 87-83 (F-OT)
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| 7.) Nevada | ||||
| 73-75 (F)
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| 10.) Texas | ||||
| 7.) Nevada | ||||
| 2.) Cincinnati | ||||
| 68-53 (F)
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| 2.) Cincinnati | South Region | |||
| 15.) Georgia State | ||||
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